SMPDB

Showing 120701 - 120710 of 605359 pathways

SMPDB ID	Pathway Name and Description	Pathway Class	Chemical Compounds	Proteins
SMP0143334 View Pathway	Didanosine Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Didanosine
SMP0174626 View Pathway	Didanosine Predicted Metabolism Pathway Metabolites of Didanosine are predicted with biotransformer. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic	Didanosine Didanosine PIS1M1 Didanosine PIS1M2 Heme	Cytochrome P450 1A2 Unknown
SMP0143884 View Pathway	Didecyldimethylammonium Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Didecyldimethylammonium
SMP0246158 View Pathway	Diego BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic
SMP0143324 View Pathway	Dienestrol Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Dienestrol
SMP0126541 View Pathway	Dienogest Action Pathway Dienogest is a semisynthetic progestogen derived from 19-nortestosterone and has antiandrogenic properties. This drug is used as a contraceptive or to treat endometriosis alone or combined with ethinylestradiol. Dienogest acts by binding as an agonist to the progesterone receptor with weak affinity but high specificity. This will lower the level of production of Gonadotropin hormone-releasing hormone (GnRH) in the hypothalamus. This results in the atrophy of the endometrium after prolonged use. As a contraceptive, it also acts by reducing the level of endogenous production of oestradiol, which suppresses the effects of oestradiol on both the eutopic and ectopic endometrium (anovulation). Also, since this drug is an agonist of the androgen receptor, it helps to improve androgenic symptoms like acne and hirsutism. This drug is administered as an oral tablet. BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	1,2-Diacyl-sn-glycerol (dioctadecanoyl, n-C18:0) 17-Hydroxyprogesterone 17a-Hydroxypregnenolone 17β-estradiol 2-Hydroxyestradiol 4-Hydroxyestradiol 5-Androstenediol Adenosine triphosphate Androstenedione Calcium cAMP Cholesterol Dehydroepiandrosterone Dienogest Estrone Guanosine diphosphate Heme Hydrogen Ion Inositol 1,4,5-trisphosphate Magnesium NAD NADH Oxygen PIP2(16:0/16:2(9Z,12Z)) Potassium Pregnenolone Progesterone Pyrophosphate Testosterone Water ( show all show less )	3 beta-hydroxysteroid dehydrog... Adenylate cyclase type 1 Androgen receptor ATP-sensitive inward rectifier... cAMP-dependent protein kinase ... cAMP-dependent protein kinase ... cAMP-dependent protein kinase ... cAMP-dependent protein kinase ... cAMP-dependent protein kinase ... cAMP-dependent protein kinase ... cAMP-dependent protein kinase ... Catenin beta-1 Cholesterol side-chain cleavag... Cyclic AMP-dependent transcrip... Cytochrome P450 19A1 Cytochrome P450 1A1 Cytochrome P450 1B1 Early growth response protein ... Estradiol 17-beta-dehydrogenas... Follicle-stimulating hormone r... Follitropin subunit beta Follitropin subunit beta Glycoprotein hormones alpha ch... Glycoprotein hormones alpha ch... Gonadotropin-releasing hormone... Guanine nucleotide-binding pro... Guanine nucleotide-binding pro... Guanine nucleotide-binding pro... Guanine nucleotide-binding pro... Gβ Gγ Inhibin alpha chain Inhibin beta A chain KiSS-1 receptor Lutropin subunit beta Lutropin-choriogonadotropic ho... Membrane-associated progestero... Metastasis-suppressor KiSS-1 Phospholipase B Progonadoliberin-1 Progonadoliberin-1 Proto-oncogene c-Fos Splicing factor 1 Steroid 17-alpha-hydroxylase/1... Steroidogenic acute regulatory... Testosterone 17-beta-dehydroge... Transcription factor AP-1 Transcription factor Sp1 ( show all show less )
SMP0145449 View Pathway	Dienogest Drug Metabolism Pathway Gadoversetamide is a drug that is not metabolized by the human body as determined by current research and biotransformer analysis. Gadoversetamide passes through the liver and is then excreted from the body mainly through the kidney. BioPAX SVG SBGN SBML PWML All files (.zip)	Metabolic	Dienogest	Solute carrier organic anion t...
SMP0144663 View Pathway	Diethylamino hydroxybenzoyl hexyl benzoate Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Diethylamino hydroxybenzoyl hexyl benzoate
SMP0143155 View Pathway	Diethylcarbamazine Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Diethylcarbamazine
SMP0143369 View Pathway	Diethylpropion Drug Metabolism Action Pathway BioPAX SVG SBGN SBML PWML All files (.zip)	Drug Action	Diethylpropion