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Pathway Description
Zuclopenthixol Dopamine Antagonist Action Pathway
Homo sapiens
Drug Action Pathway
Created: 2023-07-28
Last Updated: 2023-11-27
Zuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. Zuclopenthixol is a typical antipsychotic neuroleptic drug of the thioxanthene class. It mainly acts by antagonism of D1 and D2 dopamine receptors. Zuclopenthixol also has high affinity for alpha1-adrenergic and 5-HT2 receptors. It has weaker histamine H1 receptor blocking activity, and even lower affinity for muscarinic cholinergic and alpha2-adrenergic receptors.
References
Zuclopenthixol Dopamine Antagonist Pathway References
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Pubmed: 1975640
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