Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
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5- hydroxytryptamine receptor 2A 5- hydroxytryptamine receptor 2C Amine oxidase [flavin- containing] B Voltage- dependent P/Q-type calcium channel subunit alpha-1A Voltage- dependent L-type calcium channel subunit beta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Synaptic vesicular amine transporter Tryptophan 5-hydroxylase 1 Aromatic-L- amino-acid decarboxylase Ca+ Serotonin Serotonin Moclobemide Ca+ Serotonin Moclobemide Moclobemide L-Tryptophan Tetrahydrobiopterin O2 5-Hydroxy-L-tryptophan 4a-Hydroxytetrahydrobiopterin CO2 H2O O2 H2O2 NH3 5-Hydroxyindoleacetic acid FAD Fe2+ Pyridoxal 5'-phosphate Gq signaling cascade Synaptic Vesicle Cytosol Cytosol Presynaptic Neuron Postsynaptic Neuron Synapse Mood Improvements Serotonin is synthesized and stored in synaptic vesicles at the nerve terminal. Serotonin activates 5HT2A and 5HT2C receptors, which are responsible for mood improvements. Blood-Brain Barrier Diffusion Raphe Nucleus Moclobemide inhibits the amine oxidase A and B. This results in the decrease of the metabolism of serotonin. This inhibition results in increased levels of serotonin in the cytosol of the neurons.
HTR2A HTR2C MAOB CACNA1A CACNB1 CACNA2D2 SLC18A2 TPH1 DDC Calcium Serotonin Serotonin Moclobemide Calcium Serotonin Moclobemide Moclobemide L-Tryptophan Tetrahydrobiopterin Oxygen 5-Hydroxy-L- tryptophan 4a- Hydroxytetrahydrobiopterin Carbon dioxide Water Oxygen Hydrogen peroxide Ammonia 5- Hydroxyindoleacetic acid Gq signaling cascade