Quantitative metabolomics services for biomarker discovery and validation.
Specializing in ready to use metabolomics kits.
Your source for quantitative metabolomics technologies and bioinformatics.
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5- hydroxytryptamine receptor 6 5- hydroxytryptamine receptor 7 Sodium- dependent serotonin transporter Voltage- dependent P/Q-type calcium channel subunit alpha-1A Voltage- dependent L-type calcium channel subunit beta-1 Voltage- dependent calcium channel subunit alpha-2/delta-2 Synaptic vesicular amine transporter Unknown Tryptophan 5-hydroxylase 1 Aromatic-L- amino-acid decarboxylase Ca+ Serotonin Serotonin Amoxapine Ca+ Serotonin Amoxapine Na+ Na+ L-Tryptophan Tetrahydrobiopterin O2 5-Hydroxy-L-tryptophan 4a-Hydroxytetrahydrobiopterin CO2 Fe2+ Pyridoxal 5'-phosphate Modulate cyclic adenosine triphosphate Regulation of Fyn kinase Induction of structural plasticity cAMP Synaptic Vesicle Cytosol Cytosol Presynaptic Neuron Postsynaptic Neuron Synapse ↓ Negative symptoms of schizophrenia Serotonin is synthesized and stored in synaptic vesicles at the nerve terminal Amoxapine is a weak partial agonist at 5HT 6 and 7 receptors where it acts as a functional antagonist to reduce negative symptoms of schizophrenia ↑Cognitive Improvement Brain Raphei nuclei producing serotonergic neurons Blood vessel -blood brain barrier passive diffusion Suppression of depression and anxiety Serotonin helps with learning, memory, happiness, body temperature, sleep, sexual behaviour, and hunger, which helps supress depression and anxiety
HTR6 HTR7 SLC6A4 CACNA1A CACNB1 CACNA2D2 SLC18A2 Unknown TPH1 DDC Calcium Serotonin Serotonin Amoxapine Calcium Serotonin Amoxapine Sodium Sodium L-Tryptophan Tetrahydrobiopterin Oxygen 5-Hydroxy-L- tryptophan 4a- Hydroxytetrahydrobiopterin Carbon dioxide Modulate cyclic adenosine triphosphate Regulation of Fyn kinase Induction of structural plasticity cAMP
HTR6 HTR7 SLC6A4 CACNA1A <