Carnosine N-
methyltransferase
cytosolic
non-specific
dipeptidase
Carnosine
synthase 1
1-Methylhistidine
1-Methylhistidine
1-Methylhistidine
S-Adenosylmethionine
Carnosine
S-Adenosylhomocysteine
Anserine
H2O
β-Alanine
ATP
L-Histidine
β-Alanine
ADP
Pi
Renal clearance (excretion)
Kidney
Blood Vessel
Stomach Cell
High concentrations of
1-methylhistidine is the
results of an accumulation
of anserine from dietary
flesh sources such as high
meat consumption.