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Showing 141 - 160 of 1576 proteins

Protein ID

Protein

Pathways

P18124

View in UniProt

60S ribosomal protein L7

Gene Name: RPL7

Binds to G-rich structures in 28S rRNA and in mRNAs. Plays a regulatory role in the translation apparatus; inhibits cell-free translation of mRNAs.

P62424

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60S ribosomal protein L7a

Gene Name: RPL7A

P62917

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60S ribosomal protein L8

Gene Name: RPL8

P32969

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60S ribosomal protein L9

Gene Name: RPL9

Q9UNU6

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HMDBP06125

View in HMDB

7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase

Gene Name: CYP8B1

Involved in bile acid synthesis and is responsible for the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7 alpha, 12 alpha-dihydroxy-4-cholesten-3-one. Responsible for the balance between formation of cholic acid and chenodeoxycholic acid. Has a rather broad substrate specificity including a number of 7-alpha-hydroxylated C27 steroids.

Q9UBM7

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HMDBP00548

View in HMDB

7-dehydrocholesterol reductase

Gene Name: DHCR7

Production of cholesterol by reduction of C7-C8 double bond of 7-dehydrocholesterol (7-DHC).

Q9NRR6

View in UniProt

HMDBP01572

View in HMDB

72 kDa inositol polyphosphate 5-phosphatase

Gene Name: INPP5E

Converts phosphatidylinositol 3,4,5-trisphosphate (PtdIns 3,4,5-P3) to PtdIns-P2. Specific for lipid substrates, inactive towards water soluble inositol phosphates.

P08253

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HMDBP02804

View in HMDB

72 kDa type IV collagenase

Gene Name: MMP2

PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels

P11021

View in UniProt

78 kDa glucose-regulated protein

Gene Name: HSPA5

Q15118

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HMDBP01172

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[Pyruvate dehydrogenase [lipoamide]] kinase isozyme 1, mitochondrial

Gene Name: PDK1

Inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism

DB00054

View in DrugBank

Abciximab

Fab fragment of the chimeric human-murine monoclonal antibody 7E3. Abciximab binds to the glycoprotein (GP) IIb/IIIa receptor of human platelets and inhibits platelet aggregation by preventing the binding of fibrinogen, von Willebrand factor and other adhesive molecules.

Q9BWD1

View in UniProt

HMDBP00013

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Acetyl-CoA acetyltransferase, cytosolic

Gene Name: ACAT2

P24752

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HMDBP00038

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Acetyl-CoA acetyltransferase, mitochondrial

Gene Name: ACAT1

Plays a major role in ketone body metabolism.

Q13085

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HMDBP00047

View in HMDB

Acetyl-CoA carboxylase 1

Gene Name: ACACA

Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Q9NUB1

View in UniProt

HMDBP00042

View in HMDB

Acetyl-coenzyme A synthetase 2-like, mitochondrial

Gene Name: ACSS1

Important for maintaining normal body temperature during fasting and for energy homeostasis. Essential for energy expenditure under ketogenic conditions (By similarity). Converts acetate to acetyl-CoA so that it can be used for oxidation through the tricarboxylic cycle to produce ATP and CO(2).

Q9NR19

View in UniProt

HMDBP00037

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Acetyl-coenzyme A synthetase, cytoplasmic

Gene Name: ACSS2

Activates acetate so that it can be used for lipid synthesis or for energy generation.

P22303

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HMDBP00524

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Acetylcholinesterase

Gene Name: ACHE

Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.

P46597

View in UniProt

HMDBP00101

View in HMDB

Acetylserotonin O-methyltransferase

Gene Name: ASMT

Isoform 1 catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2 and isoform 3 lack enzyme activity.

Q99798

View in UniProt

HMDBP00725

View in HMDB

Aconitate hydratase, mitochondrial

Gene Name: ACO2

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity).

P60709

View in UniProt

Actin, cytoplasmic 1

Gene Name: ACTB

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
Showing 141 - 160 of 1576 proteins